Oh Baby! The Science of Identical Triplets and Quadruplets (2024)

Oh Baby! The Science of Identical Triplets and Quadruplets (1)

For two Baltimore parents, their three new bundles of joy may make them feel like one in a million, and statistics show they're not far off: Parents Thomas and Kristen Hewitt welcomed a rare set of identical triplets earlier this month, The Baltimore Sun reports.

The Hewitts' three boys were born more than six weeks early, on Oct. 6, the Sun reported. But having identical triplets is exceedingly rare, said Dr. Jonathan Herman, an OB-GYN at Long Island Jewish Medical Center in New Hyde Park, New York, who was not involved in the triplets' care.

Statistics help tell the story: Without the help of fertility treatments, and according to a mathematical rule that doctors use called Hellin's law, about one in 90 births is twins, one in 8,100 births (90 squared) is triplets and one in 729,000 births (90 cubed) is quadruplets, Herman said. [Seeing Double: 8 Fascinating Facts About Twins]

However, these numbers include both identical and fraternal babies. Identical siblings are much more rare: Only about one in 250 births is identical twins, according to a 2003 study in the Journal of Biosocial Science. Identical triplets are even less common, occurring about 20 to 30 times per 1 million births, the study found.

During the past few decades, fertility treatments have led to a rise in the rate of twins and other multiple births. For instance, the twin birth rate in the United States has increased more than 75 percent since 1980, and the triplet and high-order multiple births increased at an even higher rate, according to the U.S. Department of Health and Human Services.

In 2013, there were about 132,300 twin births, about 4,300 triplet births, 270 quadruplet births, and 66 births of quintuplets or higher-order births, out of about 3.9 million total births in the United States, according to the Centers for Disease Control and Prevention.

How it happens

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There are two main ways twin births occur. In the case of fraternal twins, a woman's ovaries release two eggs at the same time, which are then fertilized by two separate sperm. These babies develop at the same time within the womb, but the two children have the same degree of genetic similarity as any siblings, sharing about 50 percent of their genes.

Identical twins arise via a different route: A single sperm cell fertilizes a single egg, but then the single resulting cell splits into two identical cells, which have the same chromosomes. From this point on, the embryos may grow differently depending on their environments, but their DNA remains the same, Herman said.

In the case of identical triplets or quadruplets, the single fertilized egg splits into three or four genetically identical eggs, Herman said.

It's unknown why a fertilized egg sometimes splits, but identical twins tend to run in families, indicating that there's a genetic component, Herman said.

Researchers have also found some other hints: Studies show that older, as well as larger and taller women are more likely to have twins. The people of certain ethnic groups, including the Yoruba people of central Africa, are also more likely to have twins, whereas other groups, such as people in Asia and Central America, are less likely to have multiple births, a 2011 study in the journal PLOS ONE found.

But these numbers are only for surviving multiples; sometimes, the fetuses of multiple pregnancies don't survive to birth.

"The more babies you have [at once], the more dangerous it is," Herman told Live Science. "There's a saying that twins are twice as much fun for the family, but three times as much trouble for doctors."

Births involving twins, triplets and quadruplets often have complications, including prematurity and low birth weight, Herman said. In those with a condition called twin-twin transfusion, one fetus siphons blood from the other, and is born with ruddy skin, while the other is pale and scrawny, Herman said. Women who carry multiples also have a greater risk of gestational diabetes, according to the American Society for Reproductive Medicine.

But the public continues to be fascinated with twins, and stories about identical triplets, quadruplets and quintuplets tend to make the news.

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Such births also make a lot of work for parents. To tell their kids apart, the Hewitts have given each of their three boys differently colored strings to wear on their wrists and ankles, according to the Sun. And Kristen, a cosmetologist, plans to cut the boys' hair in different ways.

But her husband, Thomas, chuckled at the idea, according to the Sun, saying that it "will work, until they realize they can buzz each other's heads."

Follow Laura Geggel on Twitter @LauraGeggel. Follow Live Science @livescience, Facebook& Google+. Original article on Live Science.

Oh Baby! The Science of Identical Triplets and Quadruplets (2)

Laura Geggel

Editor

Laura is the archaeology and Life's Little Mysteries editor at Live Science. She also reports on general science, including paleontology. Her work has appeared in The New York Times, Scholastic, Popular Science and Spectrum, a site on autism research. She has won multiple awards from the Society of Professional Journalists and the Washington Newspaper Publishers Association for her reporting at a weekly newspaper near Seattle. Laura holds a bachelor's degree in English literature and psychology from Washington University in St. Louis and a master's degree in science writing from NYU.

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Oh Baby! The Science of Identical Triplets and Quadruplets (2024)

FAQs

Is there such a thing as identical triplets or quadruplets? ›

Identical triplets or quadruplets are very rare and result when the original fertilized egg splits and then one of the resultant cells splits again (for triplets) or, even more rarely, a further split occurs (for quadruplets).

How many identical quadruplets exist? ›

There are roughly 72 documented cases of spontaneous identical quadruplets in medical history. Spontaneous means that the babies were conceived without reproductive assistance.

How rare are twins triplets and quadruplets? ›

Naturally, twins occur in about one in 250 pregnancies, triplets in about one in 10,000 pregnancies, and quadruplets in about one in 700,000 pregnancies. The main factor that increases your chances of having a multiple pregnancy is the use of infertility treatment, but there are other factors.

How many triplets are possible? ›

Thus, the number of triplets is infinite.

How many babies can a woman have naturally at once? ›

What was the largest number of babies ever in a woman's womb? Mr. BEAM: Well, it's fair to say there's no limit per se, but the largest number ever recorded was 15. And that's quindecaplets that were recorded in 1971.

Is it possible to have 5 babies at once? ›

The occurrence of quintuplets pregnancies and births of higher order is rare. Twins are the most common type of multiple pregnancy. The most famous quintuplets are the Dionne quintuplets born in Canada in 1934. The sisters Annette, Émilie, Yvonne, Cécile, and Marie were immensely popular.

Who are the quadruplets born in 2024? ›

The last of quadruplets born on leap year day to a couple from northern Saskatchewan has joined her three siblings and parents at a temporary home in Saskatoon. Savannah Ratt and Gilbert Merasty welcomed Aleah, Beautiful, Cecelia and Dominick on Feb. 29, 2024.

Has anyone naturally conceived quadruplets? ›

The couple conceived quadruplets naturally, an extremely rare occurrence that happens in just 1 in 700,000 pregnancies. Approximately 90 percent of quadruplets are conceived with the assistance of medical technology.

Are triplets possible naturally? ›

Multiple births (delivering twins, triplets or more) is common with fertility treatments. But the couple conceived naturally. Spontaneous triplets are rare, occurring in 1 in almost 7,000 pregnancies. Other data puts the chances even lower, with naturally occurring triplets occurring in 1 in 10,000 pregnancies.

What race is most likely to have triplets? ›

White people assigned female at birth have the highest rate of higher-order multiple births (triplets or more). This is especially true for those older than 35.

What race has the most twins? ›

High parity – Having one or more previous pregnancies, especially a multiple pregnancy, increases the chances of having multiples. Race – African-American women are more likely to have twins than any other race. Asian and Native Americans have the lowest twinning rates.

What is a MoMo pregnancy? ›

Monoamniotic twins are identical or semi-identical twins that share the same amniotic sac within their mother's uterus. Monoamniotic twins are always monochorionic and are usually termed Monoamniotic-Monochorionic ("MoMo" or "Mono Mono") twins. They share the placenta, but have two separate umbilical cords.

What gender can triplets be? ›

The majority of triplets are what is known as trizygotic. This is because they are formed when three separate, individual eggs are fertilised by three separate sperm. These babies share the same characteristics as any other siblings with the same biological parents. They can be the same or opposite genders.

Will triplets ever be made? ›

The sequel to 1988's Twins starring Danny DeVito and Arnold Schwarzenegger, titled Triplets, announced in 2021 is now dead. Director Ivan Reitman was set to return and Tracy Morgan was going to play a new, third member of the unlikely brotherhood.

What is the longest you can carry triplets? ›

Twin pregnancies occasionally progress to 40 weeks but almost always deliver early. As the number of fetuses increases, the expected duration of the pregnancy decreases. The average duration is 35 weeks for twins, 33 weeks for triplets, and 29 weeks for quadruplets.

Are there any identical triplets in the world? ›

Research on the prevalence of monozygotic triplets varies. A 2012 case report of a healthy set of spontaneously conceived identical triplet boys lists the incidence at 1 in 100,000 live births. 1 Most reported cases are conceived through assisted reproductive techniques.

What are 4 triplets called? ›

Quadruplets

Has there ever been any conjoined triplets? ›

In addition to some historical descriptions, only three attested clinical cases of symmetric conjoined triplets have been published to date (Athanasiadis, Tzannatos, Mikos, Zafrakas, & Bontis, 2005; Reina, 1841; Rode et al., 2006), which will be discussed in detail below.

Do identical quintuplets exist? ›

The Dionne quintuplets (born 28 May 1934, near Corbeil, Ontario, Canada) were the first quintuplets known to survive infancy. The five girls (Yvonne, Annette, Cecile, Emilie and Marie) were also the only set of identical quintuplets known to live into adulthood.

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